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IL31 polyclonal antibody

  • Catalog # : PAB13184
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IL31.
  • Immunogen:
  • A synthetic peptide corresponding to internal region 18 amino acids of human IL31.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (2.5-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 3.
  • Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.
    Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA.Nat Immunol. 2004 Jul;5(7):752-60. Epub 2004 Jun 6.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of IL31 in human skeletal muscle tissue lysate with IL31 polyclonal antibody (Cat # PAB13184) at (A) 2.5, (B) 5 and (C) 10 ug/mL .
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • IL31
  • Gene Alias:
  • IL-31
  • Gene Description:
  • interleukin 31
  • Gene Summary:
  • IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM
  • Other Designations:
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