ATG7 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of ATG7 in Caco-2 cell lysate with ATG7 polyclonal antibody (Cat # PAB13169) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Immunocytochemistry
Immunocytochemistry of ATG7 in MCF-7 cells with ATG7 polyclonal antibody (Cat # PAB13169) at 10 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ATG7.
Immunogen
A synthetic peptide corresponding to C-terminus 17 amino acids of human ATG7.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ATG7 in Caco-2 cell lysate with ATG7 polyclonal antibody (Cat # PAB13169) at (A) 0.5, (B) 1 and (C) 2 ug/mL .Immunocytochemistry
Immunocytochemistry of ATG7 in MCF-7 cells with ATG7 polyclonal antibody (Cat # PAB13169) at 10 ug/mL . -
Gene Info — ATG7
Entrez GeneID
10533Protein Accession#
NP_006386Gene Name
ATG7
Gene Alias
APG7-LIKE, APG7L, DKFZp434N0735, GSA7
Gene Description
ATG7 autophagy related 7 homolog (S. cerevisiae)
Omim ID
608760Gene Ontology
HyperlinkGene Summary
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. [provided by RefSeq
Other Designations
APG7 autophagy 7-like|ubiquitin activating enzyme E1-like protein
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Interactome
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Pathway
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Disease
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Publication Reference
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Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A.
Oncogene 2004 Apr; 23(16):2891.
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Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y.
Journal of Cellular Biology 2000 Sep; 150(6):1507.
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Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO.
Carcinogenesis 1993 Dec; 14(12):2501.
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Autophagy as a cell death and tumor suppressor mechanism.
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