AES polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of AES in 293 cell lysate with AES polyclonal antibody (Cat # PAB13166) at (A) 2 and (B) 4 ug/mL .
Immunocytochemistry
Immunocytochemistry of AES in 293 cells with AES polyclonal antibody (Cat # PAB13166) at 10 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AES.
Immunogen
A synthetic peptide corresponding to N-terminus 16 amino acids of human AES.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of AES in 293 cell lysate with AES polyclonal antibody (Cat # PAB13166) at (A) 2 and (B) 4 ug/mL .Immunocytochemistry
Immunocytochemistry of AES in 293 cells with AES polyclonal antibody (Cat # PAB13166) at 10 ug/mL . -
Gene Info — AES
Entrez GeneID
166Protein Accession#
NP_945320Gene Name
AES
Gene Alias
AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Gene Description
amino-terminal enhancer of split
Omim ID
600188Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Publication Reference
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Regulation of Bcl-2 proteins during anoikis and amorphosis.
Martin SS, Vuori K.
Biochimica et Biophysica Acta 2004 Jul; 1692(2-3):145.
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A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors.
Jan Y, Matter M, Pai JT, Chen YL, Pilch J, Komatsu M, Ong E, Fukuda M, Ruoslahti E.
Cell 2004 Mar; 116(5):751.
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Groucho/TLE family proteins and transcriptional repression.
Chen G, Courey AJ.
Gene 2000 May; 249(1-2):1.
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Regulation of Bcl-2 proteins during anoikis and amorphosis.
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