Irak2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Irak2.
Immunogen
A synthetic peptide corresponding to C-terminus 16 amino acids of mouse Irak2.
Host
Rabbit
Reactivity
Mouse
Specificity
This antibody is common to all four isoforms. Anti-mIRAK2 is mouse specific. Anti-IRAK2 has no cross response to IRAK.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Irak2 in A-20 whole cell lysate with Irak2 polyclonal antibody (Cat # PAB13162) at (A) 0.5, (B) 1, and (C) 2 ug/mL . -
Gene Info — Irak2
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Publication Reference
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The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory.
Hardy MP, O'Neill LA.
The Journal of Biological Chemistry 2004 Jun; 279(26):27699.
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Signaling events induced by lipopolysaccharide-activated toll-like receptor 2.
Yang RB, Mark MR, Gurney AL, Godowski PJ.
The Journal of Immunology 1999 Jul; 163(2):639.
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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.
Muzio M, Ni J, Feng P, Dixit VM.
Science 1997 Nov; 278(5343):1612.
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The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory.
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