CBLN1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CBLN1.
Immunogen
A synthetic peptide corresponding to internal region 15 amino acids of human CBLN1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of CBLN1 in mouse cerebellum tissue lysate with CBLN1 polyclonal antibody (Cat # PAB13160) at (A) 2 and (B) 4 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of rat brain tissue using CBLN1 polyclonal antibody (Cat # PAB13160) at 2 ug/mL . -
Gene Info — CBLN1
Entrez GeneID
869Protein Accession#
P23435Gene Name
CBLN1
Gene Alias
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Gene Description
cerebellin 1 precursor
Omim ID
600432Gene Ontology
HyperlinkGene Summary
This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq
Other Designations
cerebellin 1
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Disease
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Publication Reference
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Integration of growth factor and nutrient signaling: implications for cancer biology.
Shamji AF, Nghiem P, Schreiber SL.
Molecular Cell 2003 Aug; 12(2):271.
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Cerebellin stimulates the secretory activity of the rat adrenal gland: in vitro and in vivo studies.
Albertin G, Malendowicz LK, Macchi C, Markowska A, Nussdorfer GG.
Neuropeptides 2000 Feb; 34(1):7.
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Cerebellin enhances in vitro secretory activity of human adrenal gland.
Mazzocchi G, Andreis PG, De Caro R, Aragona F, Gottardo L, Nussdorfer GG.
The Journal of Clinical Endocrinology and Metabolism 1999 Feb; 84(2):632.
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Integration of growth factor and nutrient signaling: implications for cancer biology.
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