TSC1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TSC1.
Immunogen
A synthetic peptide corresponding to internal region 15 amino acids of human TSC1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
TSC1 antibody will recognize both isoforms of TSC1.
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of TSC1 in EL4 cell lysate with TSC1 polyclonal antibody (Cat # PAB13145) at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.Immunocytochemistry
Immunocytochemistry of TSC1 in EL4 cells with TSC1 polyclonal antibody (Cat # PAB13145) at 2 ug/mL -
Gene Info — TSC1
Entrez GeneID
7248Protein Accession#
AAC51674Gene Name
TSC1
Gene Alias
KIAA0243, LAM, MGC86987, TSC
Gene Description
tuberous sclerosis 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000022439|hamartin|tuberous sclerosis 1 protein|tumor suppressor
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Signaling by target of rapamycin proteins in cell growth control.
Inoki K, Ouyang H, Li Y, Guan KL.
Microbiology and Molecular Biology Reviews: MMBR 2005 Mar; 69(1):79.
-
Integration of growth factor and nutrient signaling: implications for cancer biology.
Shamji AF, Nghiem P, Schreiber SL.
Molecular Cell 2003 Aug; 12(2):271.
-
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Inoki K, Li Y, Xu T, Guan KL.
Genes & Development 2003 Jul; 17(15):1829.
-
Signaling by target of rapamycin proteins in cell growth control.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com