TRAF3IP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TRAF3IP2 expression in human lung (lane A) and placenta (lane B) tissue lysates with TRAF3IP2 polyclonal antibody (Cat # PAB13101) at 1 ug /mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of TRAF3IP2 in human lung tissue with TRAF3IP2 polyclonal antibody (Cat # PAB13101) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TRAF3IP2.
Immunogen
A synthetic peptide corresponding to amino acids 2-15 of human TRAF3IP2.
Sequence
PPQLQETRMNRSIP
Host
Rabbit
Reactivity
Human
Specificity
A band at approximately 63 KDa can be detected.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TRAF3IP2 expression in human lung (lane A) and placenta (lane B) tissue lysates with TRAF3IP2 polyclonal antibody (Cat # PAB13101) at 1 ug /mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of TRAF3IP2 in human lung tissue with TRAF3IP2 polyclonal antibody (Cat # PAB13101) at 5 ug/mL . -
Gene Info — TRAF3IP2
Entrez GeneID
10758Protein Accession#
AF274303Gene Name
TRAF3IP2
Gene Alias
ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581
Gene Description
TRAF3 interacting protein 2
Omim ID
607043Gene Ontology
HyperlinkGene Summary
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq
Other Designations
NFkB-activating protein ACT1|OTTHUMP00000017022|OTTHUMP00000017024|OTTHUMP00000040422|connection to IKK and SAPK/JNK
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Interactome
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Disease
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Publication Reference
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CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.
Leonardi A, Chariot A, Claudio E, Cunningham K, Siebenlist U.
PNAS 2000 Sep; 97(19):10494.
Application：WB-Ce, WB-Tr, Human, HeLa, Jurkat cells.
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Act1, an NF-kappa B-activating protein.
Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR.
PNAS 2000 Sep; 97(19):10489.
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CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.
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