IL27RA polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of IL27RA expression in human spleen tissue lysates with IL27RA polyclonal antibody (Cat # PAB13096) at 1 ug /mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of IL27RA in human spleen tissue with IL27RA polyclonal antibody (Cat # PAB13096) at 10 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL27RA.
Immunogen
A synthetic peptide corresponding to N-terminus of human IL27RA.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of IL27RA expression in human spleen tissue lysates with IL27RA polyclonal antibody (Cat # PAB13096) at 1 ug /mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of IL27RA in human spleen tissue with IL27RA polyclonal antibody (Cat # PAB13096) at 10 ug/mL . -
Gene Info — IL27RA
Entrez GeneID
9466Protein Accession#
NP_004834Gene Name
IL27RA
Gene Alias
CRL1, IL27R, TCCR, WSX1, zcytor1
Gene Description
interleukin 27 receptor, alpha
Omim ID
605350Gene Ontology
HyperlinkGene Summary
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq
Other Designations
T-cell cytokine receptor type 1|class I cytokine receptor
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Interactome
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Disease
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Publication Reference
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Development of Th1-type immune responses requires the type I cytokine receptor TCCR.
Chen Q, Ghilardi N, Wang H, Baker T, Xie MH, Gurney A, Grewal IS, de Sauvage FJ.
Nature 2000 Oct; 407(6806):916.
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Cloning and characterization of a novel class I cytokine receptor.
Sprecher CA, Grant FJ, Baumgartner JW, Presnell SR, Schrader SK, Yamagiwa T, Whitmore TE, O'Hara PJ, Foster DF.
Biochemical and Biophysical Research Communications 1998 May; 246(1):82.
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Development of Th1-type immune responses requires the type I cytokine receptor TCCR.
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