AVEN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AVEN.
Immunogen
A synthetic peptide corresponding to 18 amino acids near N-terminus of human AVEN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of AVEN in Raji cell lysate with AVEN polyclonal antibody (Cat # PAB13093) at 1 ug/mL in (A) the presence and (B) the absence of blocking peptide.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of AVEN in human spleen tissue with AVEN polyclonal antibody (Cat # PAB13093) at 5 ug/mL . -
Gene Info — AVEN
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Interactome
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Disease
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Publication Reference
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Survivin and aven: two distinct antiapoptotic signals in acute leukemias.
Paydas S, Tanriverdi K, Yavuz S, Disel U, Sahin B, Burgut R.
Annals of Oncology 2003 Jul; 14(7):1045.
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Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.
Chau BN, Cheng EH, Kerr DA, Hardwick JM.
Molecular Cell 2000 Jul; 6(1):31.
Application:IP, WB-Ce, WB-Tr, Human, Monkey, HeLa, COS-1 cells.
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Cell death in the third millennium.
Lockshin RA, Osborne B, Zakeri Z.
Cell Death and Differentiation 2000 Jan; 7(1):2.
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Survivin and aven: two distinct antiapoptotic signals in acute leukemias.
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