Diablo polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of Diablo in mouse heart tissue lysate in the absence (A) or presence (B) of blocking peptide and in rat heart tissue lysate (C) with Diablo polyclonal antibody (Cat # PAB13090) at 1 ug /mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of mouse spleen tissue using Diablo polyclonal antibody (Cat # PAB13090) at 2 ug/mL .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Diablo.
Immunogen
A synthetic peptide corresponding to amino acids 222-237 of mouse Diablo.
Sequence
SDEGADQEEEAYLRED
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western blot analysis of Diablo in mouse heart tissue lysate in the absence (A) or presence (B) of blocking peptide and in rat heart tissue lysate (C) with Diablo polyclonal antibody (Cat # PAB13090) at 1 ug /mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of mouse spleen tissue using Diablo polyclonal antibody (Cat # PAB13090) at 2 ug/mL . -
Gene Info — Diablo
Entrez GeneID
66593Protein Accession#
AF203914Gene Name
Diablo
Gene Alias
0610041G12Rik, AU040403, Smac
Gene Description
diablo homolog (Drosophila)
Gene Ontology
HyperlinkOther Designations
OTTMUSP00000031733|diablo|direct IAP binding protein with low PI|second mitochondria-derived activator of caspase
-
Interactome
-
Publication Reference
-
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri T, Huang Z, Alnemri ES.
The Journal of Biological Chemistry 2000 Nov; 275(46):36152.
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO.
Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y.
Nature 2000 Aug; 406(6798):855.
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.
Du C, Fang M, Li Y, Li L, Wang X.
Cell 2000 Jul; 102(1):33.
Application：IF, WB-Ce, Human, HeLa cells.
-
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com