IRAK2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IRAK2.
Immunogen
A synthetic peptide corresponding to C-terminus of human IRAK2.
Host
Rabbit
Reactivity
Human
Specificity
A 65 KDa band can be detected. Anti-IRAK2 has no cross response to IRAK.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of IRAK2 in K-562 whole cell lysate with IRAK2 polyclonal antibody (Cat # PAB13083) at 1 : 500 dilution.Immunofluorescence
Immunofluorescence of IRAK2 in HeLa cells with IRAK2 polyclonal antibody (Cat # PAB13083) at 10 ug/mL . -
Gene Info — IRAK2
Entrez GeneID
3656Protein Accession#
AAO24761Gene Name
IRAK2
Gene Alias
IRAK-2, MGC150550
Gene Description
interleukin-1 receptor-associated kinase 2
Omim ID
603304Gene Ontology
HyperlinkGene Summary
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq
Other Designations
interleukin-1 receptor associated kinase-2
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Interactome
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Pathway
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Disease
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Publication Reference
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Signaling events induced by lipopolysaccharide-activated toll-like receptor 2.
Yang RB, Mark MR, Gurney AL, Godowski PJ.
The Journal of Immunology 1999 Jul; 163(2):639.
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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.
Muzio M, Ni J, Feng P, Dixit VM.
Science 1997 Nov; 278(5343):1612.
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IRAK: a kinase associated with the interleukin-1 receptor.
Cao Z, Henzel WJ, Gao X.
Science 1996 Feb; 271(5252):1128.
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Signaling events induced by lipopolysaccharide-activated toll-like receptor 2.
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