GDF6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GDF6.
Immunogen
A synthetic peptide corresponding to C-terminus 17 amino acids of human GDF6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of GDF6 in SK-N-SH lysate with GDF6 polyclonal antibody (Cat # PAB13050) at (A) 0.5 and (B) 1 ug/mL . -
Gene Info — GDF6
Entrez GeneID
392255Protein Accession#
NP_001001557Gene Name
GDF6
Gene Alias
BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1
Gene Description
growth differentiation factor 6
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation. [provided by RefSeq
Other Designations
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Pathway
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Disease
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Publication Reference
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Eye and neural defects associated with loss of GDF6.
Hanel ML, Hensey C.
BMC Developmental Biology 2006 Sep; 6:43.
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Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member.
McPherron AC, Lawler AM, Lee SJ.
Nature 1997 May; 387(6628):83.
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The transforming growth factor-beta family.
Massague J.
Annual Review of Cell Biology 1990 Jan; 6:597.
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Eye and neural defects associated with loss of GDF6.
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