WNT10A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of WNT10A.
Immunogen
A synthetic peptide corresponding to C-terminus 14 amino acids of human WNT10A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of WNT10A in Raw 264.7 cell lysate with WNT10A polyclonal antibody (Cat # PAB13043) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemical staining of human skeletal muscle tissue with 10 ug/mL WNT10A polyclonal antibody (Cat # PAB13043). -
Gene Info — WNT10A
Entrez GeneID
80326Protein Accession#
Q9GZT5Gene Name
WNT10A
Gene Alias
FLJ14301
Gene Description
wingless-type MMTV integration site family, member 10A
Gene Ontology
HyperlinkGene Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq
Other Designations
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Interactome
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Publication Reference
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Expression of WNT10A in human cancer.
Kirikoshi H, Inoue S, Sekihara H, Katoh M.
International Journal of Oncology 2001 Nov; 19(5):997.
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WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.
Kirikoshi H, Sekihara H, Katoh M.
Biochemical and Biophysical Research Communications 2001 May; 283(4):798.
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Expression of wnt10a in the central nervous system of developing zebrafish.
Kelly GM, Lai CJ, Moon RT.
Developmental Biology 1993 Jul; 158(1):113.
Application:IHC, WB, Fish, Zebrafish central nervous system.
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Expression of WNT10A in human cancer.
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