DLGAP4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DLGAP4.
Immunogen
A synthetic peptide corresponding to internal region 13 amino acids of human DLGAP4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of DLGAP4 in SK-N-SH cell lysate with DLGAP4 polyclonal antibody (Cat # PAB13042) at 1 ug/mL . -
Gene Info — DLGAP4
Entrez GeneID
22839Protein Accession#
NP_055717Gene Name
DLGAP4
Gene Alias
DAP4, KIAA0964, MGC131862, RP5-977B1.6, SAPAP4
Gene Description
discs, large (Drosophila) homolog-associated protein 4
Gene Ontology
HyperlinkGene Summary
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000030861|OTTHUMP00000030863|PSD-95/SAP90 binding protein 4|SAP90/PSD-95-associated protein 4|disks large associated protein 4|disks large-associated protein 4
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Interactome
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Disease
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Publication Reference
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FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.
Bongiorno-Borbone L, Kadare G, Benfenati F, Girault JA.
Biochemical and Biophysical Research Communications 2005 Sep; 337(2):641.
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Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA.
Kindler S, Rehbein M, Classen B, Richter D, Bockers TM.
Brain Research. Molecular Brain Research 2004 Jul; 126(1):14.
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Positional cloning and characterisation of the human DLGAP2 gene and its exclusion in progressive epilepsy with mental retardation.
Ranta S, Zhang Y, Ross B, Takkunen E, Hirvasniemi A, de la Chapelle A, Gilliam TC, Lehesjoki AE.
European Journal of Human Genetics 2000 May; 8(5):381.
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FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.
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