FGF4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of FGF4 in NIH NIH/3T3 cell lysate with FGF4 polyclonal antibody (Cat # PAB13022) at (A) 0.5 and (B) 1 ug/mL .
Immunocytochemistry
Immunocytochemical staining of BALB/3T3 cells with 2.5 ug/mL FGF4 polyclonal antibody (Cat # PAB13022).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FGF4.
Immunogen
A synthetic peptide corresponding to C-terminus 18 amino acids of human FGF4.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of FGF4 in NIH NIH/3T3 cell lysate with FGF4 polyclonal antibody (Cat # PAB13022) at (A) 0.5 and (B) 1 ug/mL .Immunocytochemistry
Immunocytochemical staining of BALB/3T3 cells with 2.5 ug/mL FGF4 polyclonal antibody (Cat # PAB13022). -
Gene Info — FGF4
Entrez GeneID
2249Protein Accession#
P08620Gene Name
FGF4
Gene Alias
HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF
Gene Description
fibroblast growth factor 4
Omim ID
164980Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq
Other Designations
heparin secretory transforming protein 1|human stomach cancer, transforming factor from FGF-related oncogene|kaposi sarcoma oncogene|oncogene HST|transforming protein KS3
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Interactome
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Pathway
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Disease
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Publication Reference
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Fibroblast growth factors, their receptors and signaling.
Powers CJ, McLeskey SW, Wellstein A.
Endocrine-Related Cancer 2000 Sep; 7(3):165.
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Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud.
Laufer E, Nelson CE, Johnson RL, Morgan BA, Tabin C.
Cell 1994 Dec; 79(6):993.
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An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family.
Delli Bovi P, Curatola AM, Kern FG, Greco A, Ittmann M, Basilico C.
Cell 1987 Aug; 50(5):729.
Application：IP, Monkey, COS cells.
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Fibroblast growth factors, their receptors and signaling.
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