ZBP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of ZBP1 in mouse small intestine tissue lysate with ZBP1 polyclonal antibody (Cat # PAB13018) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Immunohistochemistry
Immunohistochemical staining of human small intestine tissue with 2.5 ug/mL ZBP1 polyclonal antibody (Cat # PAB13018).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ZBP1.
Immunogen
A synthetic peptide corresponding to C-terminus 18 amino acids of human ZBP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ZBP1 in mouse small intestine tissue lysate with ZBP1 polyclonal antibody (Cat # PAB13018) at (A) 0.5, (B) 1 and (C) 2 ug/mL .Immunohistochemistry
Immunohistochemical staining of human small intestine tissue with 2.5 ug/mL ZBP1 polyclonal antibody (Cat # PAB13018). -
Gene Info — ZBP1
Entrez GeneID
81030Protein Accession#
EAW75510Gene Name
ZBP1
Gene Alias
C20orf183, DAI, DLM-1, DLM1
Gene Description
Z-DNA binding protein 1
Omim ID
606750Gene Ontology
HyperlinkGene Summary
DLM1 encodes a Z-DNA binding protein. Z-DNA formation is a dynamic process, largely controlled by the amount of supercoiling.[supplied by OMIM
Other Designations
OTTHUMP00000031373|tumor stroma and activated macrophage protein DLM-1
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Interactome
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Publication Reference
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.
Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T.
Nature 2007 Jul; 448(7152):501.
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Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins.
Schwartz T, Behlke J, Lowenhaupt K, Heinemann U, Rich A.
Nature Structural Biology 2001 Sep; 8(9):761.
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Cloning of DLM-1, a novel gene that is up-regulated in activated macrophages, using RNA differential display.
Fu Y, Comella N, Tognazzi K, Brown LF, Dvorak HF, Kocher O.
Gene 1999 Nov; 240(1):157.
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.
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