GRIK5 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of GRIK5 in human brain tissue lysate with GRIK5 polyclonal antibody (Cat # PAB13016) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue using GRIK5 polyclonal antibody (Cat # PAB13016) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GRIK5.
Immunogen
A synthetic peptide corresponding to C-terminus 17 amino acids of human GRIK5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of GRIK5 in human brain tissue lysate with GRIK5 polyclonal antibody (Cat # PAB13016) at (A) 0.5, (B) 1 and (C) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue using GRIK5 polyclonal antibody (Cat # PAB13016) at 2.5 ug/mL . -
Gene Info — GRIK5
Entrez GeneID
2901Protein Accession#
NP_002079Gene Name
GRIK5
Gene Alias
EAA2, GRIK2, KA2
Gene Description
glutamate receptor, ionotropic, kainate 5
Omim ID
600283Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. [provided by RefSeq
Other Designations
excitatory amino acid receptor 2|glutamate receptor KA2
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Interactome
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Pathway
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Disease
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Publication Reference
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Kainate receptors.
Pinheiro P, Mulle C.
Cell and Tissue Research 2006 Jul; 326(2):457.
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Identification of an endoplasmic reticulum-retention motif in an intracellular loop of the kainate receptor subunit KA2.
Nasu-Nishimura Y, Hurtado D, Braud S, Tang TT, Isaac JT, Roche KW.
The Journal of Neuroscience 2006 Jun; 26(26):7014.
Application：IS, WB-Tr, Human, HeLa-Tac-KA2, HeLa-Tac-KA2CtermA/B, HeLa-KA2, HeLa-KA2loop, HeLa-KA2CtermA/B, HeLa-KA2loop/CtermA/B, HEK293-KA2, HEK293-KA2loop, HEK293-KA2CtermA/B, HEK293-KA2loop/CtermA/B cells.
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The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits.
Herb A, Burnashev N, Werner P, Sakmann B, Wisden W, Seeburg PH.
Neuron 1992 Apr; 8(4):775.
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Kainate receptors.
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