BRE polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of BRE in HeLa cell lysate in (A) the absence and (B) presence of blocking peptide with BRE polyclonal antibody (Cat # PAB13011) at 1 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of BRE in human brain tissue with BRE polyclonal antibody (Cat # PAB13011) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BRE.
Immunogen
A synthetic peptide corresponding to N-terminus 18 amino acids of human BRE.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of BRE in HeLa cell lysate in (A) the absence and (B) presence of blocking peptide with BRE polyclonal antibody (Cat # PAB13011) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of BRE in human brain tissue with BRE polyclonal antibody (Cat # PAB13011) at 2.5 ug/mL . -
Gene Info — BRE
Entrez GeneID
9577Protein Accession#
NP_004890Gene Name
BRE
Gene Alias
BRCC4, BRCC45
Gene Description
brain and reproductive organ-expressed (TNFRSF1A modulator)
Omim ID
610497Gene Ontology
HyperlinkGene Summary
subunit 4|OTTHUMP00000123504|OTTHUMP00000123506|OTTHUMP00000123508
Other Designations
BRCA1/BRCA2-containing complex, subunit 4|OTTHUMP00000123504|OTTHUMP00000123506|OTTHUMP00000123508
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Interactome
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Disease
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Publication Reference
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BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma.
Chan BC, Ching AK, To KF, Leung JC, Chen S, Li Q, Lai PB, Tang NL, Shaw PC, Chan JY, James AE, Lai KN, Lim PL, Lee KK, Chui YL.
Oncogene 2008 Feb; 27(9):1208.
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Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R.
Molecular Cell 2003 Nov; 12(5):1087.
Application：WB-Tr, Human, HEK 293 cells.
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Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid.
Li L, Yoo H, Becker FF, Ali-Osman F, Chan JY.
Biochemical and Biophysical Research Communications 1995 Jan; 206(2):764.
Application：WB-Ce, WB-Ti, WB-Tr, Rat, HL-60 cells, Rat tissues, U-251 cells.
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BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma.
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