FAM175A polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of FAM175A in mouse small intestine tissue lysate in (A) the absence and (B) presence of blocking peptide with FAM175A polyclonal antibody (Cat # PAB13010) at 1 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of FAM175A in human breast tissue with FAM175A polyclonal antibody (Cat # PAB13010) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FAM175A.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids of human FAM175A.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of FAM175A in mouse small intestine tissue lysate in (A) the absence and (B) presence of blocking peptide with FAM175A polyclonal antibody (Cat # PAB13010) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of FAM175A in human breast tissue with FAM175A polyclonal antibody (Cat # PAB13010) at 5 ug/mL . -
Gene Info — FAM175A
Entrez GeneID
84142Protein Accession#
NP_620775Gene Name
FAM175A
Gene Alias
ABRA1, CCDC98, FLJ11520, FLJ12642, FLJ13614
Gene Description
family with sequence similarity 175, member A
Omim ID
611143Gene Ontology
HyperlinkGene Summary
O
Other Designations
abraxas protein|coiled-coil domain containing 98
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Interactome
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Disease
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Publication Reference
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CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.
Kim H, Huang J, Chen J.
Nature Structural & Molecular Biology 2007 Aug; 14(8):710.
Application：IP, WB, Human, HEK 293T, HeLa cells.
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CCDC98 targets BRCA1 to DNA damage sites.
Liu Z, Wu J, Yu X.
Nature Structural & Molecular Biology 2007 Jul; 14(8):716.
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Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ.
Science 2007 May; 316(5828):1194.
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CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.
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