STEAP3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of STEAP3.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids of human STEAP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of STEAP3 in rat liver tissue lysate with STEAP3 polyclonal antibody (Cat # PAB13008) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of STEAP3 in mouse liver tissue with STEAP3 polyclonal antibody (Cat # PAB13008) at 2.5 ug/mL . -
Gene Info — STEAP3
Entrez GeneID
55240Protein Accession#
AAH95421Gene Name
STEAP3
Gene Alias
STMP3, TSAP6, dudlin-2
Gene Description
STEAP family member 3
Omim ID
609671Gene Ontology
HyperlinkOther Designations
1010001D01Rik|OTTHUMP00000162092|OTTHUMP00000162093|dudlin 2|dudulin 2|six transmembrane prostate protein 3|tumor suppressor pHyde
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Interactome
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Pathway
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Disease
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Publication Reference
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Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism.
Lane DJ, Chikhani S, Richardson V, Richardson DR.
Biochimica et Biophysica Acta 2013 Jun; 1833(6):1527.
Application:WB, Human, SK-Mel-28 cells.
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Liver iron transport.
Graham RM, Chua AC, Herbison CE, Olynyk JK, Trinder D.
World Journal of Gastroenterology 2007 Sep; 13(35):4725.
Application:WB-Tr, Human, HEK 293T cells.
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The Steap proteins are metalloreductases.
Ohgami RS, Campagna DR, McDonald A, Fleming MD.
Blood 2006 Aug; 108(4):1388.
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Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.
Ohgami RS, Campagna DR, Greer EL, Antiochos B, McDonald A, Chen J, Sharp JJ, Fujiwara Y, Barker JE, Fleming MD.
Nature Genetics 2005 Oct; 37(11):1264.
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Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism.
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