MORF4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of MORF4 in K-562 cell lysate with MORF4 polyclonal antibody (Cat # PAB13005) at (A) 1 and (B) 2 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of MORF4 in human brain tissue with MORF4 polyclonal antibody (Cat # PAB13005) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MORF4.
Immunogen
A synthetic peptide corresponding to N-terminus 18 amino acids of human MORF4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MORF4 in K-562 cell lysate with MORF4 polyclonal antibody (Cat # PAB13005) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of MORF4 in human brain tissue with MORF4 polyclonal antibody (Cat # PAB13005) at 5 ug/mL . -
Gene Info — MORF4
Entrez GeneID
10934Protein Accession#
Q9Y690Gene Name
MORF4
Gene Alias
CSR, CSRB, SEN, SEN1
Gene Description
mortality factor 4
Omim ID
116960Gene Ontology
HyperlinkGene Summary
Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.[supplied by OMIM
Other Designations
senescence (cellular)-related 1|senescence-related, cellular, 1
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Interactome
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Publication Reference
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Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.
Yochum GS, Ayer DE.
Molecular and Cellular Biology 2002 Nov; 22(22):7868.
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Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes.
Bertram MJ, Bérubé NG, Hang-Swanson X, Ran Q, Leung JK, Bryce S, Spurgers K, Bick RJ, Baldini A, Ning Y, Clark LJ, Parkinson EK, Barrett JC, Smith JR, Pereira-Smith OM.
Molecular and Cellular Biology 1999 Feb; 19(2):1479.
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Genetic analysis of indefinite division in human cells: identification of four complementation groups.
Pereira-Smith OM, Smith JR.
PNAS 1988 Aug; 85(16):6042.
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Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.
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