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Last updated: 2016/12/4
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HAP1 polyclonal antibody

  • Catalog # : PAB12994
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HAP1.
  • Immunogen:
  • A synthetic peptide corresponding to internal region 19 amino acids of human HAP1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of HAP1 in mouse brain tissue lysate with HAP1 polyclonal antibody (Cat # PAB12994) at (A) 0.5 and (B) 1 ug/mL .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry of HAP1 in human brain tissue with HAP1 polyclonal antibody (Cat # PAB12994) at 2.5 ug/mL .
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9001
  • Gene Name:
  • HAP1
  • Gene Alias:
  • HAP2,HIP5,HLP,hHLP1
  • Gene Description:
  • huntingtin-associated protein 1
  • Gene Summary:
  • Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000164747,huntingtin-associated protein 2,neuroan 1
  • Gene Pathway
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