NRN1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NRN1 in Daudi cell lysate with NRN1 polyclonal antibody (Cat # PAB12989) at (A) 5 and (B) 10 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of NRN1 in mouse heart tissue with NRN1 polyclonal antibody (Cat # PAB12989) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NRN1.
Immunogen
A synthetic peptide corresponding to internal region 20 amino acids of human NRN1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NRN1 in Daudi cell lysate with NRN1 polyclonal antibody (Cat # PAB12989) at (A) 5 and (B) 10 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of NRN1 in mouse heart tissue with NRN1 polyclonal antibody (Cat # PAB12989) at 5 ug/mL . -
Gene Info — NRN1
Entrez GeneID
51299Protein Accession#
NP_057672Gene Name
NRN1
Gene Alias
MGC44811, NRN, dJ380B8.2
Gene Description
neuritin 1
Omim ID
607409Gene Ontology
HyperlinkGene Summary
This gene is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000015989|neuritin
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Interactome
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Publication Reference
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Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones.
Marron TU, Guerini V, Rusmini P, Sau D, Brevini TA, Martini L, Poletti A.
Journal of Neurochemistry 2005 Jan; 92(1):10.
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In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury.
Di Giovanni S, De Biase A, Yakovlev A, Finn T, Beers J, Hoffman EP, Faden AI.
The Journal of Biological Chemistry 2005 Jan; 280(3):2084.
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Some assembly required: the development of neuronal synapses.
Li Z, Sheng M.
Nature Reviews. Molecular Cell Biology 2003 Nov; 4(11):833.
Application：WB, Human, Mammalian cells.
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Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones.
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