SCO1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SCO1.
Immunogen
A synthetic peptide corresponding to internal region 14 amino acids of human SCO1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western blot analysis of SCO1 in human brain tissue lysate with SCO1 polyclonal antibody (Cat # PAB12983) at (A) 0.5 and (B) 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of SCO1 in human brain tissue with SCO1 polyclonal antibody (Cat # PAB12983) at 2.5 ug/mL . -
Gene Info — SCO1
Entrez GeneID
6341Protein Accession#
O75880Gene Name
SCO1
Gene Alias
SCOD1
Gene Description
SCO cytochrome oxidase deficient homolog 1 (yeast)
Omim ID
603644Gene Ontology
HyperlinkGene Summary
Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq
Other Designations
cytochrome oxidase deficient homolog 1
-
Interactome
-
Disease
-
Publication Reference
-
Human Sco1 functional studies and pathological implications of the P174L mutant.
Banci L, Bertini I, Ciofi-Baffoni S, Leontari I, Martinelli M, Palumaa P, Sillard R, Wang S.
PNAS 2007 Jan; 104(1):15.
-
Human Sco1 and Sco2 function as copper-binding proteins.
Horng YC, Leary SC, Cobine PA, Young FB, George GN, Shoubridge EA, Winge DR.
The Journal of Biological Chemistry 2005 Oct; 280(40):34113.
Application:WB, Human, Human skin fibroblasts.
-
SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae.
Glerum DM, Shtanko A, Tzagoloff A.
The Journal of Biological Chemistry 1996 Aug; 271(34):20531.
Application:WB-Re, WB-Tr, Yeast, Recombinant proteins, Yeast cells.
-
Human Sco1 functional studies and pathological implications of the P174L mutant.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com