TARBP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of TARBP1 in NIH/3T3 cell lysate with TARBP1 polyclonal antibody (Cat # PAB12981) at (A) 1 and (B) 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TARBP1.
Immunogen
A synthetic peptide corresponding to internal region 17 amino acids of human TARBP1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TARBP1 in NIH/3T3 cell lysate with TARBP1 polyclonal antibody (Cat # PAB12981) at (A) 1 and (B) 2 ug/mL . -
Gene Info — TARBP1
Entrez GeneID
6894Protein Accession#
NP_005637Gene Name
TARBP1
Gene Alias
FLJ30482, TRM3, TRP-185, TRP185
Gene Description
TAR (HIV-1) RNA binding protein 1
Omim ID
605052Gene Ontology
HyperlinkGene Summary
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000036048|TAR (HIV) RNA binding protein 1|TAR (HIV) RNA-binding protein 1|TAR RNA binding protein 1|TAR RNA loop binding protein
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Interactome
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Disease
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Publication Reference
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Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA.
Wu-Baer F, Lane WS, Gaynor RB.
The Journal of Biological Chemistry 1996 Feb; 271(8):4201.
Application：Func, Human, HeLa cells.
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Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA.
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