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Last updated: 2017/4/23
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CBL polyclonal antibody

  • Catalog # : PAB12976
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CBL.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus 14 amino acids of human CBL.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of CBL in Daudi cell lysate with CBL polyclonal antibody (Cat # PAB12976) at (A) 0.5, (B) 1, and (C) 2 ug/mL .
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence of CBL in human lymph node tissue with CBL polyclonal antibody (Cat # PAB12976) at 20 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 867
  • Gene Name:
  • CBL
  • Gene Alias:
  • C-CBL,CBL2,RNF55
  • Gene Description:
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence
  • Gene Summary:
  • The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
  • Other Designations:
  • oncogene CBL2
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