TNFRSF12A polyclonal antibody
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Specification
Product Description
Rabbit Polyclonal antibody raised against recombinant TNFRSF12A.
Immunogen
Recombinant Fc fusion protein corresponding to human TNFRSF12A.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of TNFRSF12A in (A) mock- and (B) TNFRSF12A-GPI-transfected 293 cells with TNFRSF12A polyclonal antibody (Cat # PAB12972) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of TNFRSF12A in human liver tissue with TNFRSF12A polyclonal antibody (Cat # PAB12972) at 2.5 ug/mL . -
Gene Info — TNFRSF12A
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Interactome
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Publication Reference
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The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.
Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA.
The Biochemical Journal 2003 Apr; 371(Pt 2):395.
Application:WB-Tr, Insect, Sf9 cells.
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The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas.
Feng SL, Guo Y, Factor VM, Thorgeirsson SS, Bell DW, Testa JR, Peifley KA, Winkles JA.
The American Journal of Pathology 2000 Apr; 156(4):1253.
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TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.
Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, Garcia I, Browning JL.
The Journal of Biological Chemistry 1997 Dec; 272(51):32401.
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The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.
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