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Last updated: 2017/9/24
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TNFSF12 polyclonal antibody

  • Catalog # : PAB12960
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  • Specification
  • Product Description:
  • Rabbit Polyclonal antibody raised against recombinant TNFSF12.
  • Immunogen:
  • Recombinant protein corresponding to human TNFSF12.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of (A) 5 ng, (B) 25 ng and (C) 50 ng of recombinant TNFSF12 with TNFSF12 polyclonal antibody (Cat # PAB12960) at 1 ug/mL .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry of TNFSF12 in human brain tissue with TNFSF12 polyclonal antibody (Cat # PAB12960) at 10 ug/mL .
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8742
  • Gene Name:
  • TNFSF12
  • Gene Alias:
  • APO3L,DR3LG,MGC129581,MGC20669,TWEAK
  • Gene Description:
  • tumor necrosis factor (ligand) superfamily, member 12
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq
  • Other Designations:
  • APO3/DR3 ligand,TNF-related WEAK inducer of apoptosis
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