LAMP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of LAMP1 in EL4 cell lysate with LAMP1 polyclonal antibody (Cat # PAB12957) at (A) 1 and (B) 2 ug/mL .
Immunofluorescence
Immunofluorescence of LAMP1 in human colon tissue with LAMP1 polyclonal antibody (Cat # PAB12957) at 20 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LAMP1.
Immunogen
A synthetic peptide corresponding to internal region 15 amino acids of human LAMP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Despite its predicted size, LAMP-1 migrates at 110KDa in SDS-PAGE.
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for up to one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of LAMP1 in EL4 cell lysate with LAMP1 polyclonal antibody (Cat # PAB12957) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunofluorescence
Immunofluorescence of LAMP1 in human colon tissue with LAMP1 polyclonal antibody (Cat # PAB12957) at 20 ug/mL . -
Gene Info — LAMP1
Entrez GeneID
3916Protein Accession#
NP_005552Gene Name
LAMP1
Gene Alias
CD107a, LAMPA, LGP120
Gene Description
lysosomal-associated membrane protein 1
Omim ID
153330Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq
Other Designations
OTTHUMP00000040663
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Interactome
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Pathway
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Publication Reference
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Distinguishing human peripheral blood CD16+ myeloid cells based on phenotypic characteristics.
Fromm PD, Silveira PA, Hsu JL, Papadimitrious MS, Lo TH, Ju X, Kupresanin F, Romano A, Hsu WH, Bryant CE, Kong B, Abadir E, Mekkawy A, M McGuire H, Groth BFS, Cunningham I, Newman E, Gibson J, Hogarth PM, Hart DNJ, Clark GJ.
Journal of Leukocyte Biology 2020 Feb; 107(2):323.
Application：IF, Human, Dendritic cells, Monocytes.
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Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A.
Oncogene 2004 Apr; 23(16):2891.
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Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y.
Journal of Cellular Biology 2000 Sep; 150(6):1507.
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Identification of two lysosomal membrane glycoproteins.
Chen JW, Murphy TL, Willingham MC, Pastan I, August JT.
The Journal of Cell Biology 1985 Jul; 101(1):85.
Application：IEM, IF, IP, Mouse, HaNIH, NIH/3T3, P388D1 cells.
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Distinguishing human peripheral blood CD16+ myeloid cells based on phenotypic characteristics.
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