NGFR polyclonal antibody
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of (A) 25 ng, (B) 50 ng, and (C) 100 ng of purified recombinant NGFR with NGFR polyclonal antibody (Cat # PAB12953) at 1 ug/mL .
Immunocytochemistry
Immunocytochemistry of NGFR in A-20 cells with NGFR polyclonal antibody (Cat # PAB12953) at 10 ug/mL .
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Specification
Product Description
Rabbit Polyclonal antibody raised against recombinant NGFR.
Immunogen
Recombinant protein corresponding to human NGFR.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of (A) 25 ng, (B) 50 ng, and (C) 100 ng of purified recombinant NGFR with NGFR polyclonal antibody (Cat # PAB12953) at 1 ug/mL .Immunocytochemistry
Immunocytochemistry of NGFR in A-20 cells with NGFR polyclonal antibody (Cat # PAB12953) at 10 ug/mL . -
Gene Info — NGFR
Entrez GeneID
4804Protein Accession#
NP_002498Gene Name
NGFR
Gene Alias
CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
Gene Description
nerve growth factor receptor (TNFR superfamily, member 16)
Omim ID
162010Gene Ontology
HyperlinkGene Summary
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq
Other Designations
low affinity nerve growth factor receptor|low-affinity nerve growth factor receptor|nerve growth factor receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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The p75 neurotrophin receptor: multiple interactors and numerous functions.
Gentry JJ, Barker PA, Carter BD.
Progress in Brain Research 2004 Jan; 46:25.
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Regulation of proliferation, survival and apoptosis by members of the TNF superfamily.
Gaur U, Aggarwal BB.
Biochemical Pharmacology 2003 Oct; 66(8):1403.
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Expression and structure of the human NGF receptor.
Johnson D, Lanahan A, Buck CR, Sehgal A, Morgan C, Mercer E, Bothwell M, Chao M.
Cell 1986 Nov; 47(4):545.
Application：WB-Tr, Mouse, Mouse fibroblasts, PC-12 cells.
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The p75 neurotrophin receptor: multiple interactors and numerous functions.
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