TNFSF18 polyclonal antibody
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of (A) 5 ng, (B) 25 ng, and (C) 50 ng of purified recombinant GITRL with TNFSF18 polyclonal antibody (Cat # PAB12952) at 1 ug/mL .
Immunocytochemistry
Immunocytochemistry of TNFSF18 in THP-1 cells with TNFSF18 polyclonal antibody (Cat # PAB12952) at 10 ug/mL .
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Specification
Product Description
Rabbit Polyclonal antibody raised against recombinant TNFSF18.
Immunogen
Recombinant protein corresponding to human TNFSF18.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of (A) 5 ng, (B) 25 ng, and (C) 50 ng of purified recombinant GITRL with TNFSF18 polyclonal antibody (Cat # PAB12952) at 1 ug/mL .Immunocytochemistry
Immunocytochemistry of TNFSF18 in THP-1 cells with TNFSF18 polyclonal antibody (Cat # PAB12952) at 10 ug/mL . -
Gene Info — TNFSF18
Entrez GeneID
8995Protein Accession#
Q9UNG2Gene Name
TNFSF18
Gene Alias
AITRL, GITRL, MGC138237, TL6, hGITRL
Gene Description
tumor necrosis factor (ligand) superfamily, member 18
Omim ID
603898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq
Other Designations
AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand
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Interactome
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Pathway
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Disease
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Publication Reference
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Regulation of proliferation, survival and apoptosis by members of the TNF superfamily.
Gaur U, Aggarwal BB.
Biochemical Pharmacology 2003 Oct; 66(8):1403.
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Role of GITR in activation response of T lymphocytes.
Ronchetti S, Nocentini G, Riccardi C, Pandolfi PP.
Blood 2002 Jul; 100(1):350.
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Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.
Gurney AL, Marsters SA, Huang RM, Pitti RM, Mark DT, Baldwin DT, Gray AM, Dowd AD, Brush AD, Heldens AD, Schow AD, Goddard AD, Wood WI, Baker KP, Godowski PJ, Ashkenazi A.
Current Biology 1999 Feb; 9(4):215.
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Regulation of proliferation, survival and apoptosis by members of the TNF superfamily.
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