CDH13 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of CDH13 in NIH/3T3 lysate with CDH13 polyclonal antibody (Cat # PAB12951) at (A) 0.5 and (B) 1 ug/mL .
Immunofluorescence
Immunofluorescence of CDH13 in K-562 cells with CDH13 polyclonal antibody (Cat # PAB12951) at 20 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDH13.
Immunogen
A synthetic peptide corresponding to 15 amino acids near N-terminus of human CDH13.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (0.5-1 ug/mL)
Immunocytochemistry (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CDH13 in NIH/3T3 lysate with CDH13 polyclonal antibody (Cat # PAB12951) at (A) 0.5 and (B) 1 ug/mL .Immunofluorescence
Immunofluorescence of CDH13 in K-562 cells with CDH13 polyclonal antibody (Cat # PAB12951) at 20 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDH13
Entrez GeneID
1012Protein Accession#
NP_001248Gene Name
CDH13
Gene Alias
CDHH
Gene Description
cadherin 13, H-cadherin (heart)
Omim ID
601364Gene Ontology
HyperlinkGene Summary
This gene is a member of the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region but, unlike the typical cadherin superfamily member, lacks the highly conserved cytoplasmic region. This particular cadherin is a putative mediator of cell-cell interaction in the heart and may act as a negative regulator of neural cell growth. The gene locus is hypermethylated or deleted in breast, ovarian and lung cancers. Two major mRNA transcripts encoding identical proteins are found, products of alternative polyadenylation sites. [provided by RefSeq
Other Designations
H-cadherin|P105|T-cad|T-cadherin|cadherin 13|heart-cadherin|truncated-cadherin
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Interactome
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Disease
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Publication Reference
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Structure and functions of classical cadherins.
Ivanov DB, Philippova MP, Tkachuk VA.
Biochemistry. Biokhimiia 2001 Oct; 66(10):1174.
Application：IHC, WB, Human, Aorta, Carotid, Hearts, Iliac, Kidney arteries.
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The H-cadherin (CDH13) gene is inactivated in human lung cancer.
Sato M, Mori Y, Sakurada A, Fujimura S, Horii A.
Human Genetics 1998 Jul; 103(1):96.
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T-cadherin, a novel cadherin cell adhesion molecule in the nervous system lacks the conserved cytoplasmic region.
Ranscht B, Dours-Zimmermann MT.
Neuron 1991 Sep; 7(3):391.
Application：WB-Ce, WB-Ti, Chicken, Chicken brain, Chicken heart, Chicken kidney, Chicken liver, Chicken muscle, Chicken retina, Chicken sympathetic neurons.
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Structure and functions of classical cadherins.
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