IRS1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of IRS1 in PC-3 cell lysate with IRS1 polyclonal antibody (Cat # PAB12949) at (A) 1, (B) 2 and (C) 4 ug/mL .
Immunocytochemistry
Immunocytochemistry of IRS1 in P815 cells with IRS1 polyclonal antibody (Cat # PAB12949) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IRS1.
Immunogen
A synthetic peptide corresponding to internal region 16 amino acids of human IRS1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of IRS1 in PC-3 cell lysate with IRS1 polyclonal antibody (Cat # PAB12949) at (A) 1, (B) 2 and (C) 4 ug/mL .Immunocytochemistry
Immunocytochemistry of IRS1 in P815 cells with IRS1 polyclonal antibody (Cat # PAB12949) at 2 ug/mL . -
Gene Info — IRS1
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Interactome
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Pathway
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Disease
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Publication Reference
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Integration of growth factor and nutrient signaling: implications for cancer biology.
Shamji AF, Nghiem P, Schreiber SL.
Molecular Cell 2003 Aug; 12(2):271.
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A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
PNAS 2001 Apr; 98(8):4640.
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Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.
Giovannone B, Scaldaferri ML, Federici M, Porzio O, Lauro D, Fusco A, Sbraccia P, Borboni P, Lauro R, Sesti G.
Diabetes/Metabolism Research and Reviews 2000 Nov; 16(6):434.
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Integration of growth factor and nutrient signaling: implications for cancer biology.
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