MTOR polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FRAP1.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids of human FRAP1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of MTOR in L1210 cell lysate with MTOR polyclonal antibody (Cat # PAB12944) at (A) 1 and (B) 2 ug/mL .Immunocytochemistry
Immunocytochemistry of MTOR in L1210 cells with MTOR polyclonal antibody (Cat # PAB12944) at 2 ug/mL . -
Gene Info — MTOR
Entrez GeneID
2475Protein Accession#
NP_004949Gene Name
MTOR
Gene Alias
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gene Description
mechanistic target of rapamycin
Omim ID
601231Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
Other Designations
FK506 binding protein 12-rapamycin associated protein 1|FK506 binding protein 12-rapamycin associated protein 2|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression.
Fingar DC, Blenis J.
Oncogene 2004 Apr; 23(18):3151.
-
Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin.
Cardenas ME, Zhu D, Heitman J.
Current Opinion in Nephrology and Hypertension 1995 Nov; 4(6):472.
Application:WB-Ce, WB-Tr, Human, Mammalian cells.
-
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH.
Cell 1994 Jul; 78(1):35.
Application:IP, WB-Re, N/A, Recombinant protein.
-
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com