TLR10 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TLR10 in human lymph node tissue lysates with TLR10 polyclonal antibody (Cat # PAB12914) at (A) 0.5 and (B) 1 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TLR10.
Immunogen
A synthetic peptide corresponding to internal region 14 amino acids of human TLR10.
Host
Rabbit
Reactivity
Human
Specificity
Despite its predicted size of ~90 KDa, a band correpsonding to TLR10 is observed at ~75 KDa in immunoblot assays.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TLR10 in human lymph node tissue lysates with TLR10 polyclonal antibody (Cat # PAB12914) at (A) 0.5 and (B) 1 ug/mL . -
Gene Info — TLR10
Entrez GeneID
81793Protein Accession#
AAQ88667Gene Name
TLR10
Gene Alias
CD290, MGC104967, MGC126398, MGC126399
Gene Description
toll-like receptor 10
Omim ID
606270Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact function is not known. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000158729
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Interactome
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Disease
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Publication Reference
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The Toll-IL-1 receptor adaptor family grows to five members.
O'Neill LA, Fitzgerald KA, Bowie AG.
Trends in Immunology 2003 Jun; 24(6):286.
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Toll-like receptors.
Takeda K, Kaisho T, Akira S.
Annual Review of Immunology 2001 Dec; 21:335.
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Innate immune recognition.
Janeway CA Jr, Medzhitov R.
Annual Review of Immunology 2001 Oct; 20:197.
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The Toll-IL-1 receptor adaptor family grows to five members.
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