APOBEC3G polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of APOBEC3G expression in Caco-2 cell lysate in the (A), absence and (B) presence of blocking peptide with APOBEC3G polyclonal antibody (Cat # PAB12912) at 5 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen using APOBEC3G polyclonal antibody (Cat # PAB12912) at 1 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of APOBEC3G.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids of human APOBEC3G.
Host
Rabbit
Reactivity
Human
Specificity
APOBEC3G antibody will also detect the APOBEC3F isoform.
Form
Liquid
Recommend Usage
Western Blot (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of APOBEC3G expression in Caco-2 cell lysate in the (A), absence and (B) presence of blocking peptide with APOBEC3G polyclonal antibody (Cat # PAB12912) at 5 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen using APOBEC3G polyclonal antibody (Cat # PAB12912) at 1 ug/mL . -
Gene Info — APOBEC3G
Entrez GeneID
60489Protein Accession#
NP_068594Gene Name
APOBEC3G
Gene Alias
ARP9, CEM15, FLJ12740, MDS019, bK150C2.7, dJ494G10.1
Gene Description
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Omim ID
607113Gene Ontology
HyperlinkGene Summary
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq
Other Designations
DNA dC->dU editing enzyme|OTTHUMP00000028911|phorbolin-like protein MDS019
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Interactome
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Pathway
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Disease
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Publication Reference
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Intrinsic immunity: a front-line defense against viral attack.
Bieniasz PD.
Nature Immunology 2004 Nov; 5(11):1109.
Application：IHC, WB, Human, Mammalian cells.
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Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein.
Sheehy AM, Gaddis NC, Choi JD, Malim MH.
Nature 2002 Aug; 418(6898):646.
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An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.
Jarmuz A, Chester A, Bayliss J, Gisbourne J, Dunham I, Scott J, Navaratnam N.
Genomics 2002 Mar; 79(3):285.
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Intrinsic immunity: a front-line defense against viral attack.
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