Casp12 large polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Casp12.
Immunogen
A synthetic peptide corresponding to mouse Casp12 large peptide.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Caspase-12 (large) antibody can be used for the detection of both the propeptide and cleaved forms of caspase-12
Form
Liquid
Recommend Usage
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of Casp12 (large) in human heart lysate with Casp12 large polyclonal antibody (Cat # PAB12908) at 0.5 (lane A), 1 (lane B), and 2 ug/mL (lane C), respectively.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human heart tissue using Casp12 large polyclonal antibody (Cat # PAB12908) at 2 ug/mL . -
Gene Info — Casp12
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Publication Reference
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Caspases find a new place to hide.
Mehmet H.
Nature 2000 Jan; 403(6765):29.
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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J.
Nature 2000 Jan; 403(6765):98.
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Characterization of seven murine caspase family members.
Van de Craen M, Vandenabeele P, Declercq W, Van den Brande I, Van Loo G, Molemans F, Schotte P, Van Criekinge W, Beyaert R, Fiers W.
FEBS Letters 1997 Feb; 403(1):61.
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Caspases find a new place to hide.
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