SEPT4 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SEPT4 expression in human lung (lane 1), spleen (lane 2), and kidney (lane 3) tissue lysates with SEPT4 polyclonal antibody (Cat # PAB12882) at 2 ug /mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of SEPT4 in human lung tissue with SEPT4 polyclonal antibody (Cat # PAB12882) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SEPT4.
Immunogen
A synthetic peptide corresponding to N-terminus of human SEPT4.
Host
Rabbit
Reactivity
Human
Specificity
A band at 32 KDa can be detected.
Form
Liquid
Recommend Usage
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SEPT4 expression in human lung (lane 1), spleen (lane 2), and kidney (lane 3) tissue lysates with SEPT4 polyclonal antibody (Cat # PAB12882) at 2 ug /mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of SEPT4 in human lung tissue with SEPT4 polyclonal antibody (Cat # PAB12882) at 2 ug/mL . -
Gene Info — SEPT4
Entrez GeneID
5414Protein Accession#
AAG45673Gene Name
SEPT4
Gene Alias
ARTS, BRADEION, CE5B3, H5, MART, PNUTL2, SEP4, hCDCREL-2, hucep-7
Gene Description
septin 4
Omim ID
603696Gene Ontology
HyperlinkGene Summary
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. The protein encoded by this gene is thought to be part of a complex involved in cytokinesis. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
cell division control-related protein 2|cerebral protein 7|peanut-like 2|septin-M
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Interactome
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Disease
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Publication Reference
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A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.
Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, Gottfried Y, Birkey Reffey S, de Caestecker MP, Danielpour D, Book-Melamed N, Timberg R, Duckett CS, Lechleider RJ, Steller H, Orly J, Kim SJ, Roberts AB.
Nature Cell Biology 2000 Dec; 2(12):915.
Application：IF, IHC, WB-Ce, Human, Monkey, Rat, COS, NRP-154, A549 cells, Cardiomyoctes.
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The ARTS of apoptosis.
Depraetere V.
Nature Cell Biology 2000 Dec; 2(12):E219.
Application：IF, Drosophila, Drosophila.
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Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene.
Paavola P, Horelli-Kuitunen N, Palotie A, Peltonen L.
Genomics 1999 Jan; 55(1):122.
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A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.
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