NDEL1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NDEL1 in Jurkat whole cell lysate with NDEL1 polyclonal antibody (Cat # PAB12877) at 0.5, 1, and 2 ug/mL .
Immunocytochemistry
Immunocytochemistry of NDEL1 in Jurkat cells with NDEL1 polyclonal antibody (Cat # PAB12877) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NDEL1.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids of human NDEL1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NDEL1 in Jurkat whole cell lysate with NDEL1 polyclonal antibody (Cat # PAB12877) at 0.5, 1, and 2 ug/mL .Immunocytochemistry
Immunocytochemistry of NDEL1 in Jurkat cells with NDEL1 polyclonal antibody (Cat # PAB12877) at 2 ug/mL . -
Gene Info — NDEL1
Entrez GeneID
81565Protein Accession#
AAF97497Gene Name
NDEL1
Gene Alias
DKFZp451M0318, EOPA, MITAP1, NUDEL
Gene Description
nudE nuclear distribution gene E homolog (A. nidulans)-like 1
Omim ID
607538Gene Ontology
HyperlinkGene Summary
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
NUDE-like protein|endooligopeptidase A|mitosin-associated protein MITAP1|nudE nuclear distribution gene E homolog like 1
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Interactome
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Disease
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Publication Reference
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Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein.
Liang Y, Yu W, Li Y, Yang Z, Yan X, Huang Q, Zhu X.
The Journal of Cell Biology 2004 Feb; 164(4):557.
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Cyclin-dependent kinase 5 and neuronal migration in the neocortex.
Gupta A, Tsai LH.
Neuro-Signals 2003 Sep; 12(4-5):173.
Application：WB, Human, Mammalian cells.
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Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.
Liu Z, Steward R, Luo L.
Nature Cell Biology 2000 Nov; 2(11):776.
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Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein.
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