CARD9 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of CARD9 expression in human MDA-MB-361 (A) and PC-3 (B) cell lysate with CARD9 polyclonal antibody (Cat # PAB12874) at 2.5 ug /mL .
Immunocytochemistry
Immunocytochemistry of CARD9 in K-562 cells with CARD9 polyclonal antibody (Cat # PAB12874) at 10 ug/mL .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CARD9.
Immunogen
A synthetic peptide corresponding to amino acids 521-536 of human CARD9.
Sequence
DRENTTGSDNTDTEGS
Host
Rabbit
Reactivity
Human
Specificity
The sequence is different from that of rat origin by two amino acids. A band at approximately 59 KDa can be detected.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of CARD9 expression in human MDA-MB-361 (A) and PC-3 (B) cell lysate with CARD9 polyclonal antibody (Cat # PAB12874) at 2.5 ug /mL .Immunocytochemistry
Immunocytochemistry of CARD9 in K-562 cells with CARD9 polyclonal antibody (Cat # PAB12874) at 10 ug/mL . -
Gene Info — CARD9
Entrez GeneID
64170Protein Accession#
AF311287Gene Name
CARD9
Gene Alias
hCARD9
Gene Description
caspase recruitment domain family, member 9
Omim ID
607212Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq
Other Designations
OTTHUMP00000022571|caspase recruitment domain protein 9
-
Interactome
-
Disease
-
Publication Reference
-
Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians.
Gavino C, Hamel N, Zeng JB, Legault C, Guiot MC, Chankowsky J, Lejtenyi D, Lemire M, Alarie I, Dufresne S, Boursiquot JN, McIntosh F, Langelier M, Behr MA, Sheppard DC, Foulkes WD, Vinh DC.
The Journal of Allergy and Clinical Immunology 2016 Apr; 137(4):1178.
Application：IP-WB, Human, HEK 293T cells.
-
CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B.
Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES.
The Journal of Biological Chemistry 2000 Dec; 275(52):41082.
Application：WB-Ce, WB-Tr, Human, 293T, THP1 cell.
-
Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com