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Last updated: 2016/12/4
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CASP14 polyclonal antibody

  • Catalog # : PAB12873
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CASP14.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus 16 amino acids of human CASP14.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 2.
  • Interleukin-18.
    Gracie JA, Robertson SE, McInnes IB.J Leukoc Biol. 2003 Feb;73(2):213-24.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of CASP14 in Jurkat cell lysate in the (A) absence or (B) presence of blocking peptide with CASP14 polyclonal antibody (Cat # PAB12873) at 1 ug/mL .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry of CASP14 in human liver tissue with CASP14 polyclonal antibody (Cat # PAB12873) at 2.5 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • CASP14
  • Gene Alias:
  • MGC119078,MGC119079
  • Gene Description:
  • caspase 14, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq
  • Other Designations:
  • apoptosis-related cysteine protease,caspase 14,caspase 14, apoptosis-related cysteine protease
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