NKIRAS2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NKIRAS2 in Raw 264.7 cell lysate with NKIRAS2 polyclonal antibody (Cat # PAB12871) at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NKIRAS2.
Immunogen
A synthetic peptide corresponding to C-terminus 14 amino acids of human NKIRAS2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NKIRAS2 in Raw 264.7 cell lysate with NKIRAS2 polyclonal antibody (Cat # PAB12871) at 1 ug/mL in the (A) absence and (B) presence of blocking peptide. -
Gene Info — NKIRAS2
Entrez GeneID
28511Protein Accession#
NP_060065Gene Name
NKIRAS2
Gene Alias
DKFZp434N1526, KBRAS2, MGC74742, kappaB-Ras2
Gene Description
NFKB inhibitor interacting Ras-like 2
Omim ID
604497Gene Ontology
HyperlinkOther Designations
I-kappa-B-interacting Ras-like protein 2|NFKB inhibitor interacting Ras-like protein 2|OTTHUMP00000164764|OTTHUMP00000164765
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Interactome
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Disease
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Publication Reference
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KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes.
Chen Y, Wu J, Ghosh G.
The Journal of Biological Chemistry 2003 Jun; 278(25):23101.
Application：IP, WB-Tr, Human, HEK 293 cells.
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A subclass of Ras proteins that regulate the degradation of IkappaB.
Fenwick C, Na SY, Voll RE, Zhong H, Im SY, Lee JW, Ghosh S.
Science 2000 Feb; 287(5454):869.
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KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes.
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