NKIRAS1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NKIRAS1.
Immunogen
A synthetic peptide corresponding to C-terminus 15 amino acids of human NKIRAS1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NKIRAS1 in Raw 264.7 cell lysate with NKIRAS1 polyclonal antibody (Cat # PAB12870) at 0.5, 1 and 2 ug/mL .Immunocytochemistry
Immunocytochemistry of NKIRAS1 in Raw 264.7 cells with NKIRAS1 polyclonal antibody (Cat # PAB12870) at 1 ug/mL . -
Gene Info — NKIRAS1
Entrez GeneID
28512Protein Accession#
AAF34998Gene Name
NKIRAS1
Gene Alias
KBRAS1, kappaB-Ras1
Gene Description
NFKB inhibitor interacting Ras-like 1
Omim ID
604496Gene Ontology
HyperlinkOther Designations
I-kappa-B-interacting Ras-like protein 1|NFKB inhibitor interacting Ras-like protein 1|kappa B-ras 1
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Interactome
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Disease
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Publication Reference
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KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes.
Chen Y, Wu J, Ghosh G.
The Journal of Biological Chemistry 2003 Jun; 278(25):23101.
Application:IP, WB-Tr, Human, HEK 293 cells.
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A subclass of Ras proteins that regulate the degradation of IkappaB.
Fenwick C, Na SY, Voll RE, Zhong H, Im SY, Lee JW, Ghosh S.
Science 2000 Feb; 287(5454):869.
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KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes.
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