TNFRSF13B polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of TNFRSF13B in K-562 (A) and U-937 (B) cell lysates with TNFRSF13B polyclonal antibody (Cat # PAB12862) at 5 ug/mL .
Immunocytochemistry
Immunocytochemistry of TNFRSF13B in K-562 cells with TNFRSF13B polyclonal antibody (Cat # PAB12862) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF13B.
Immunogen
A synthetic peptide corresponding to N-terminus of human TNFRSF13B.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (2-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TNFRSF13B in K-562 (A) and U-937 (B) cell lysates with TNFRSF13B polyclonal antibody (Cat # PAB12862) at 5 ug/mL .Immunocytochemistry
Immunocytochemistry of TNFRSF13B in K-562 cells with TNFRSF13B polyclonal antibody (Cat # PAB12862) at 2 ug/mL . -
Gene Info — TNFRSF13B
Entrez GeneID
23495Protein Accession#
NP_036584Gene Name
TNFRSF13B
Gene Alias
CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B
Gene Description
tumor necrosis factor receptor superfamily, member 13B
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
Other Designations
OTTHUMP00000065442|transmembrane activator and CAML interactor|tumor necrosis factor receptor 13B
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Interactome
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Pathway
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Disease
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Publication Reference
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BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.
Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, Soppet D, Charters M, Gentz R, Parmelee D, Li Y, Galperina O, Giri J, Roschke V, Nardelli B, Carrell J, Sosnovtseva S, Greenfield W, Ruben SM, Olsen HS, Fikes J, Hilbert DM.
Science 1999 Jul; 285(5425):260.
Application：Flow Cyt, Human, Human monocytes.
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BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, Ambrose C, Lawton P, Bixler S, Acha-Orbea H, Valmori D, Romero P, Werner-Favre C, Zubler RH, Browning JL, Tschopp J.
The Journal of Experimental Medicine 1999 Jun; 189(11):1747.
Application：Flow Cyt, Human, HEK 293 cells.
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Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase.
Mukhopadhyay A, Ni J, Zhai Y, Yu GL, Aggarwal BB.
The Journal of Biological Chemistry 1999 Jun; 274(23):15978.
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BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.
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