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Last updated: 2016/12/4
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TBK1 polyclonal antibody

  • Catalog # : PAB12859
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TBK1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus 17 amino acids of human TBK1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • A 84 KDa band should be detected. It is human, mouse and rat reactive and has no cross response to IKKa, IKKb, IKKy, or IKKe.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemistry of TBK1 in MOLT 4 cells with TBK1 polyclonal antibody (Cat # PAB12859) at 10 ug/mL .
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • TBK1
  • Gene Alias:
  • FLJ11330,NAK,T2K
  • Gene Description:
  • TANK-binding kinase 1
  • Gene Summary:
  • The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq
  • Other Designations:
  • NF-kB-activating kinase
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