DAPK2 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DAPK2.
Immunogen
A synthetic peptide corresponding to C-terminus of human DAPK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
The sequence of this antigenic peptide is identical to the corresponding amino acids of mouse origin. An approximately 42 KDa band can be detected. DAPK2 has no cross responses to DAPK1.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of DAPK2 in A-431 (H), mouse spleen (M), and rat kidney (R) lysates with DAPK2 polyclonal antibody (Cat # PAB12854) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of DAPK2 in mouse spleen cells with DAPK2 polyclonal antibody (Cat # PAB12854) at 2 ug/mL . -
Gene Info — DAPK2
Entrez GeneID
23604Protein Accession#
BAA88063Gene Name
DAPK2
Gene Alias
DRP-1, MGC119312
Gene Description
death-associated protein kinase 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq
Other Designations
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Interactomes
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Pathways
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Publication Reference
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Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.
Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A.
Molecular and Cellular Biology 2000 Feb; 20(3):1044.
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Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity.
Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ, Jenkins NA, Akira S.
Oncogene 1999 Jun; 18(23):3471.
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Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.
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