TNFRSF10D polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF10D.
Immunogen
A synthetic peptide corresponding to amino acids 249-263 of human TNFRSF10D.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TNFRSF10D in HeLa whole cell lysate with TNFRSF10D polyclonal antibody (Cat # PAB12831) at 1 : 1000 dilution.Immunocytochemistry
Immunocytochemistry staining of HeLa cells using TNFRSF10D polyclonal antibody (Cat # PAB12831) at 10 ug/mL . -
Gene Info — TNFRSF10D
Entrez GeneID
8793Protein Accession#
Q9UBN6Gene Name
TNFRSF10D
Gene Alias
CD264, DCR2, TRAILR4, TRUNDD
Gene Description
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Omim ID
603614Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq
Other Designations
TNF receptor-related receptor for TRAIL|TRAIL receptor 4|TRAIL receptor with a truncated death domain|decoy receptor 2|decoy with truncated death domain|tumor necrosis factor receptor superfamily, member 10d
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Interactome
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Pathway
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Disease
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Publication Reference
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A novel receptor for Apo2L/TRAIL contains a truncated death domain.
Marsters SA, Sheridan JP, Pitti RM, Huang A, Skubatch M, Baldwin D, Yuan J, Gurney A, Goddard AD, Godowski P, Ashkenazi A.
Current Biology 1997 Dec; 7(12):1003.
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An antagonist decoy receptor and a death domain-containing receptor for TRAIL.
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM.
Science 1997 Aug; 277(5327):815.
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The receptor for the cytotoxic ligand TRAIL.
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM.
Science 1997 Apr; 276(5309):111.
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A novel receptor for Apo2L/TRAIL contains a truncated death domain.
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