Rabbit polyclonal antibody raised against synthetic peptide of STAT1.
Immunogen:
A synthetic peptide corresponding to C-terminus of human, mouse and rat STAT1.
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Specificity:
This antibody recognizes STAT1.
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (1:50) The optimal working dilution should be determined by the end user.
Storage Buffer:
In TBS, pH 7.2 (BSA, 10% Proclin300)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations:
OTTHUMP00000165047,signal transducer and activator of transcription 1,signal transducer and activator of transcription-1,transcription factor ISGF-3 components p91/p84