JAK2 (phospho Y1007/Y1008) polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The tissue lysate derived from GH stimulated mouse liver was immunoblotted by JAK2 (phospho Y1007/Y1008) polyclonal antibody (Cat # PAB12749) at 1 : 500.
Dot Blot (Peptide)
Dot Blot : 1 ug peptide was blot onto NC membrane.
A : JAK2 (pY1007, pY1008).
B : JAK2 (Non phospho-specific).
C. Non-related Phosphopeptide.
Followed were blotted at a 1 : 2000 dilution by :
1. JAK2 (phospho Y1007/Y1008) polyclonal antibody (Cat # PAB12749).
2. JAK2 polyclonal antibody (Cat # PAB12769) (Nonphospho specific).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of JAK2.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Y1007/Y1008 of human, mouse and rat JAK2.
Sequence
EYYK
Host
Rabbit
Reactivity
Human
Specificity
This antibody recognizes JAK2 with dual phosphorylated sites of Tyr1007/1008. It does not cross-react with non-phosphospecific peptide.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Immunohistochemistry (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In TBS, pH 7.2 (BSA, 10% Proclin300)
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
The tissue lysate derived from GH stimulated mouse liver was immunoblotted by JAK2 (phospho Y1007/Y1008) polyclonal antibody (Cat # PAB12749) at 1 : 500.Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Dot Blot (Peptide)
Dot Blot : 1 ug peptide was blot onto NC membrane.
A : JAK2 (pY1007, pY1008).
B : JAK2 (Non phospho-specific).
C. Non-related Phosphopeptide.
Followed were blotted at a 1 : 2000 dilution by :
1. JAK2 (phospho Y1007/Y1008) polyclonal antibody (Cat # PAB12749).
2. JAK2 polyclonal antibody (Cat # PAB12769) (Nonphospho specific). -
Gene Info — JAK2
Entrez GeneID
3717Gene Name
JAK2
Gene Alias
JTK10
Gene Description
Janus kinase 2 (a protein tyrosine kinase)
Gene Ontology
HyperlinkGene Summary
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq
Other Designations
Janus kinase 2|OTTHUMP00000021024|OTTHUMP00000043260|tyrosine-protein kinase JAK2
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor.
Ali S, Nouhi Z, Chughtai N, Ali S.
The Journal of Biological Chemistry 2003 Dec; 278(52):52021.
Application：WB-Tr, Human, HEK 293 cells.
-
SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com