The tissue lysate derived from human liver tissue lysate was immunoprobed by EBAG9 polyclonal antibody (Cat # PAB12726) at 1 : 500. An immunoreactive band is observed around ~32 kDa (1). The lane 2 is a negative control.
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene. [provided by RefSeq
cancer associated surface antigen,estrogen receptor binding site associated antigen 9